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Recent News Stories

Measuring vision recovery following Avastin therapy Dec 1, 2008
Macular degenerationA new study finds that optical coherence tomography (OCT) subretinal fluid measurements correleted well with visual acuity recovery following Avastin therapy for neovascular age-related macular degeneration (AMD). The advent of high-definition "spectral... Read more...
Tags: wet AMD, OCT, Avastin, vision test

Retinylamine Slows Progression of AMD-Like Condition in Mice Nov 23, 2008
Laboratory mouseAn investigational drug called retinylamine slowed the progression of a condition in mice that is very similar to age-related macular degeneration (AMD) in humans. The AMD-like condition was triggered in mice by disrupting the removal of all-trans-retinal from the retina.... Read more...
Tags: animal study, visual cycle, retinylamine, lipofuscin, AMD

Meta-analysis confirms Lucentis safety Nov 23, 2008
GenentechLucentis (ranibizumab) appears safe in the treatment of wet age-related macular degeneration (AMD), according to an analysis of 4 large clinical trials. Dr David Boyer presented these findings at the 2008 Joint Meeting of the American Academy of Ophthalmology (AAO) and the European Society of... Read more...
Tags: wet AMD, Lucentis, clinical trial

Fewer injections for wet AMD: Clinical trial update Nov 23, 2008
Intravitreal injectionMedscape has assembled updates on several ongoing clinical trials into new drugs and dosing strategies that were presented at the 2008 Joint Meeting of the American Academy of Ophthalmology and the European Society of Ophthalmology held in November. Below is a synopsis of... Read more...
Tags: Lucentis, VEGF Trap, clinical trial, wet AMD

Role of integrins in proliferative diabetic retinopathy Nov 22, 2008
DiabetesThis article investigates the role of integrins in proliferative diabetic retinopathy, and concludes that they represent a potential target for the development of new drug therapies for the disease. Integrins have also been identified as playing a role in the pathogenesis of choroidal... Read more...
Tags: CNV, integrin, diabetes

Simultaneous fluorescein angiography and indocyanine green angiography detects polypoidal choroidal vasculopathy Nov 22, 2008
Polypoidal choroidal vasculopathyA new study illustrates the value of simultaneous fluorescein angiography (FA) and indocyanine green angiography (ICGA) in detecting patients with polypoidal choroidal vasculopathy (PCV). PCV is a distinct clinical entity... Read more...
Tags: PDT, PCV, ICGA

Florida drivers vision test results in fewer auto accidents Nov 21, 2008
Highway trafficA Florida vision screening law targeting older drivers appears to be associated with a decrease in death rates despite little existing evidence linking vision and car crashes. A report in this month's issue of Archives of Ophthalmology highlights the January 2004 law... Read more...
Tags: low vision, vision test, traffic safety, automobile

Ophthotech initiates phase 1 trials for two AMD drugs Nov 21, 2008
Age-related Macular DegenerationOphthotech has recently announced the initiation of two phase 1 clinical trials for new drugs designed to treat age-related macular degeration (AMD). One drug is an anti-C5 complement factor aptamer known as ARC1905. The second drug is a monoclonal antibody... Read more...
Tags: AMD, complement, integrin

Othera receives patent for topical drug for dry AMD Nov 21, 2008
Eye DropsThe U.S. Patent and Trademark Office has issued Othera Pharmaceuticals the first patent covering a broad class of disubstituted hydroxylamine small molecules that target oxidative stress and inflammation involved in age-related macular degeneration and other ocular disorders. U.S. Patent No. 7... Read more...
Tags: dry AMD, drug delivery, antioxidants, eye drops

Enabling The Blind To Find Their Way Nov 21, 2008
GPS Device"Eyes on the future" is the mantra of the 'World Sight Day' held in October to raise awareness of blindness and vision impairment. New technologies, developed by European researchers offering the visually impaired greater independence, live up to this vision. Many of the most... Read more...
Tags: mobility, GPS, travel

Steroids protect photoreceptors after photodynamic therapy Nov 20, 2008
VisudyneA study of photodynamic therapy (PDT) in laboratory rats has found that use of steroids 1 hour before the procedure reduced photoreceptor death and improved CNV resolution 1 week after PDT. Combining PDT with steroids has been found to improve the visual outcome of the procedure, although those <... Read more...
Tags: PDT, combo therapy, steroid

Somatostatin receptor agonists inhibit retinal and choroidal neovascularization Nov 19, 2008
Laboratory mouseA new study reports that the somatostatin analogue RFE-011 effectively inhibited retinal and choroidal neovascularization in mice, and was able to penetrate the eye after topical administration. The presence of somatostatin receptors on tumour cells and on proliferating vascular... Read more...
Tags: CNV

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