Compared with combination therapy of intravitreal triamcinolone (IVTA) plus photodynamic therapy (PDT), intravitreal Avastin (IVB) plus PDT was significantly more effective in maintaining and improving visual acuity and in reducing the number of treatment for patients with retinal angiomatous proliferation (RAP), according to a new study....

Photodynamic therapy (PDT) is not effective in eyes with chronic central serous chorioretinopathy (CSC) without intense hyperfluorescence on indocyanine green angiography (ICGA), according to a new study. Central serous chorioretinopathy (CSC) is commonly seen in young or middle-aged adults as localized detachment of the neurosensory retina....

There is no difference in the visual acuity (VA) outcomes after Avastin (bevacizumab) or Lucentis (ranibizumab) treatment for AMD, according to a new study. In 2006, the United States Food and Drug Administration approved the use of Lucentis (ranibizumab) for the treatment of exudative AMD. Before its approval, many ophthalmologists already...

There is no significant difference the short-term efficacy and safety of intravitreal Lucentis (ranibizumab) versus Avastin (bevacizumab) in treating myopic choroidal neovascularization (CNV), according to a new study. Choroidal neovascularization (CNV) secondary to pathologic myopia causes severe visual loss in young and middle-aged patients....

A mathematical model has been developed to predict the absolute risk of geographic atrophy and neovascular age-related macular degeneration (AMD) risk based on smoking history and genetic risk factors in individuals of European ancestry. Although AMD was long thought to have primarily an environmental etiology, genetic variation is now known...

Intravitreal Avastin (bevacizumab, IVB) injection as an adjunct to vitrectomy in the management of severe proliferative diabetic retinopathy (PDR) improves the anatomical and functional outcomes of surgery, according to a new study. Diabetic retinopathy is the result of microvascular retinal changes. Hyperglycemia-induced pericyte death and...

Combined intravitreal triamcinolone acetonide (IVTA) injection with intravitreal Avastin (bevacizumab, IVB) is effective in the treatment of choroidal neovascularization (CNV) associated with large retinal pigment epithelial detachment (PED) in age-related macular degeneration (AMD), according to a new study. A PED occurs when fluid enters the...

Avastin impairs phagocytic activity of retinal pigment epithelial (RPE) cells cultured in a laboratory, according to a new study. The retinal pigment epithelium (RPE) is a layer of "nurse cells" located immediately adjacent to the photoreceptors that provide the photoreceptors with nourishment and removes their waste products. The...

A study comparing the outcomes of laser treatment (LT), photodynamic therapy (PDT) with verteporfin, and intravitreal Avastin (bevacizumab) in patients with juxtafoveal choroidal neovascularization (CNV) secondary to pathologic myopia finds that Avastin offers the best functional results during a 2-year follow-up. Pathologic myopia is a major...

Albino rats develop progressive stages of retinal degeneration and CNV after long-term intense cyclic light exposure, allowing the detailed study of the pathogenesis and treatment of age-related macular degeneration (AMD), according to a new research report. Animal models of AMD that manifest some of the features of human AMD have become...

Older adults experience some benefit, but less than young adults, from training to use their peripheral vision to read text, according to a new study. Enhancing reading ability in peripheral vision is important for the rehabilitation of people with central-visual-field loss from age-related macular degeneration (AMD). Previous research has...

A single injection of triamcinolone (steroid) was as effective as 3 monthly injections of Avastin (bevacizumab) for the treatment of patients with diabetic macular edema, according to a new study. The traditional treatment for diabetic macular edema is laser photocoagulation. Both steroids and Avastin have been reported to have benefitial...