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Diabetes
Mar 27, 2011
The National electronic Library for Medicines in the European Union (EU) has published a review that summarizes the clinical trial data investigating the safety and effectiveness of Lucentis, Macugen, and Iluvien in the treatment of diabetic macular edema. Diabetic macular edema (DME) is a common manifestation of diabetic retinopathy and can...

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Age-related macular degeneration
Feb 27, 2011
Combined treatment of reduced-fluence verteporfin photodynamic therapy (PDT), intravitreal Lucentis (ranibizumab), intravitreal dexamethasone and oral minocycline for choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) was not more effective than combination therapy with standard-fluence PDT plus Lucentis,...

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Central serous chorioretinopathy
Jan 20, 2011
Central serous chorioretinopathy (CSC) is a chorioretinal disease, incompletely understood with systemic associations, a multifactorial aetiology, and a complex pathogenesis. Increased permeability from the choriocapillaris leads to focal or diffuse dysfunction of the retinal pigment epithelium causing a detachment of the neurosensory retina....

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The Iluvien insert, shown on a human finger to indicate size
Jan 20, 2011
Alimera Sciences announced that it received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for the investigational drug ILUVIEN. The FDA issued the CRL to communicate its decision that the NDA cannot be approved in its present form. The application seeks the approval to...

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Central retinal vein occlusion
Oct 25, 2010
For the better part of the last 2 decades, there has been little debate as to the preferred treatment of retinal vein occlusion. Ever since the results of the Branch Vein Occlusion Study were published in 1984, gold standard therapy has called for grid laser photocoagulation to treat vision-reducing macular edema caused by branch retinal vein...

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Visudyne
Oct 14, 2010
Triple therapy with intravitreal Avastin (bevacizumab) or Lucentis (ranibizumab), dexamethasone and verteporfin photodynamic therapy (PDT) for exudative age-related macular degeneration (AMD) results in fewer retreatments than either Avastin or Lucentis alone, according to a new study. No single therapy completely addresses all of the ways...

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The Iluvien insert, shown on a human finger to indicate size
Sep 20, 2010
The U.S. Food and Drug Administration has granted priority review status to Alimera Sciences' new drug application for its Iluvien intravitreal insert, the company announced in a press release. With the priority review status, which accelerates the FDA's standard review time from 10 months to 6 months, Alimera could receive a response for the...

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Central retinal vein occlusion
Sep 20, 2010
Macular edema due to branch retinal vein occlusion or central retinal vein occlusion can be effectively reduced using the Ozurdex dexamethasone intravitreal implant, but early treatment is mandatory, according to data from the multicenter GENEVA study. "Patients who were treated early showed a visual acuity improvement of three or more lines,...

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Central retinal vein occlusion
Aug 26, 2010
The European Medicines Agency has granted Allergan marketing authorization for its dexamethasone intravitreal implant for treating macular edema secondary to retinal vein occlusion, the company announced in a press release. With the approval, Ozurdex (dexamethasone 0.7 mg intravitreal implant) becomes the first and only therapeutic agent...

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Punctate inner choroidopathy
Aug 24, 2010
The clinical characteristics of a large series of patients with punctate inner choroidopathy (PIC) is presented in a new research report. The term punctate inner choroidopathy (PIC) was first used by Watzke et al in 1984 to describe findings in a group of 10 patients with multifocal, well-circumscribed, usually small choroidal lesions. These...

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