Pseudocysts in the retinal layers are present in about 27% of eyes with geographic atrophy (GA) attributable to age-related macular degeneration (AMD), according to a recent research report. In several studies of eyes with GA, spectral-domain optical coherence tomography (SD-OCT) shows the atrophic areas as thin and hyperreflective. This...

A new study finds that combined confocal scanning laser ophthalmoscopy (cSLO) and spectral-domain optical coherence tomography (SD-OCT) imaging provides unprecedented insight into dynamic microstructural changes of geographic atrophy (GA) enlargement that may help to better understand the pathogenesis of the disease. The factors predisposing to...

Choroidal thinning is a risk factor for myopic choroidal neovascularization (mCNV), according to a new study. The development of mCNV is characterized by serous retinal detachments and subretinal hemorrhage with fibrotic membrane formation. Intravitreal Avastin (bevacizumab) is generally injected to treat mCNV; however, only 40% to 70% of...

Torpedo maculopathy is a benign, congenital defect of the retinal pigment epithelium. This study was a retrospective, observational case series. The medical records of 13 patients, age 1–68 years, seen between 1982 and 2009 were reviewed. Patients were evaluated for lesion features and course on follow-up, visual acuity, fluorescein...

Damaged photoreceptors in eyes with resolved central serous chorioretinopathy (CSC) is associated with a poor visual prognosis, according to a new study. Central serous chorioretinopathy (CSC) is characterized by focal serous retinal detachment in the macular area. In most eyes, full recovery of visual acuity (VA) occurs following resolution of...

High-definition optical coherence tomography (HD-OCT) can replace routine fluorescein angiography (FA) in patients undergoing laser photocoagulation for macular edema, according to a recent journal article. Macular laser photocoagulation is still the gold standard therapy for macular edema due to retinal vascular pathologies. Its main goal is...

Spectral domain optical coherence tomography (SD-OCT) is superior to fluorescein angiography (FA) in detecting cystoid macular edema (CME) and its late complications, according to a new study. Optical coherence tomography (OCT) is an optical signal acquisition and processing method allowing extremely high-quality, micrometer-resolution,...

The choroid of patients with central serous chorioretinopathy (CSCR) is abnormally thick, according to a new study. CSCR is a disease of young and middle-aged adults that frequently manifests symptomatically in one eye, while up to 18% of cases may be bilateral. Research indicates that the disease process in CSCR is more diffuse and shows...

3D-OCT provided realistic anatomic maps of the retina in patients with age-related macular degneration (AMD), according to a new study. Numerous diagnostic tools such as optical coherence tomography (OCT) three-dimensional (3D)-OCT retinal thickness analysis (RTA), and topographic angiography (TAG) are being evaluated clinically, in addition to...

The choroid in highly myopic eyes is very thin and undergoes further thinning with increasing age and degree of myopia, according to a new study. High myopia is associated with excessive and progressive elongation of the globe, resulting in a variety of fundus changes that lead to visual impairment, including lacquer cracks in the Bruch...