MyVisionTest News Archive

Displaying news items tagged with drug delivery (More tags »)
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Intravitreal injection
Mar 8, 2011
To evaluate the amount of reflux and degree of pain with intravitreal injection (IVT) using 6 different types of syringes/needles and 5 techniques of scleral incision, including 3 modifications of a beveled scleral incision. The risk of serious adverse events reported after intravitreal (IVT) injection injection is low. Endophthalmitis, which...

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Liposome
Feb 26, 2011
Several new devices designed to deliver drugs to the posterior pole may address the drawbacks of current technologies, according to a speaker here. However, the technology has yet to catch up with the therapeutic need. The ideal drug delivery device would be able to deliver multiple drugs to the vitreous cavity, subretinal space or...

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Uveitis
Feb 26, 2011
The rate of endophthalmitis following intravitreal injection of anti-VEGF agents was very low during a recent study, a speaker said at the Macula 2011 meeting. In a 6-year retrospective case series, Streptococcus isolates presented three to four times more frequently after intravitreal injection than after intraocular surgery, Harry W. Flynn...

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Retinal detachment
Jan 20, 2011
To determine the incidence of rhegmatogenous retinal detachments (RD) after intravitreal injection in six high-volume centres. The risk of serious adverse events reported after intravitreal (IVT) injection injection is low. Endophthalmitis, which is infection inside the eye, is perhaps the most serious complication of IVT injection....

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The Iluvien insert, shown on a human finger to indicate size
Jan 20, 2011
Alimera Sciences announced that it received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for the investigational drug ILUVIEN. The FDA issued the CRL to communicate its decision that the NDA cannot be approved in its present form. The application seeks the approval to...

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Intravitreal injection
Jan 11, 2011
Prophylactic use of intraocular pressure (IOP)-lowering medication is ineffective in reducing the IOP spikes that often occur after intravitreal injections of Macugen (pegaptanib), Avastin (bevacizumab), and Lucentis (ranibizumab), according to a recent study. Seventy-one patients with exudative age-related macular degeneration received...

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Intravitreal injection
Nov 15, 2010
Streptococcus is isolated much more frequently from endophthalmitis cultures after intravitreal injection (IVI) of antivascular endothelial growth-factor (anti-VEGF) agents than after ocular surgery, results of a meta-analysis show. The new research was presented at the American Academy of Ophthalmology 2010 Annual Meeting. Ophthalmologists...

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Liposome
Aug 27, 2010
Researchers demonstrate that non-viral gene therapy can delay the onset of some forms of retinal degeneration and preserve vision, according to a new study. The researchers developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. "Our work shows that...

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Intravitreal injection
Aug 24, 2010
Intravitreal injections performed with a 30-gauge needle more often result in significant elevations of intraocular pressure (IOP) requiring extraction of fluid from the anterior chamber of the eye to rapidly lower the pressure, a procedure known as paracentesis, than when injections are performed using a 27-guage needle. Elevation of IOP is a...

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Intravitreal injection
May 9, 2010
Tunneled scleral injection technique causes greater short-term intraocular pressure (IOP) elevation following intravitreal Lucentis (ranibizumab). Elevation of IOP is a risk factor for glaucoma. IOP reflects a balance between the rate that fluid flows into the eye and the rate that it exits the eye. If inflow increases or outflow decreases,...

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