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fundus autofluorescence
Sep 20, 2010
Information gathered from the peripheral retina may be important for the diagnosis and management of retinal disease. In a retrospective analysis of patients referred to an imaging center for retinal imaging who agreed to have wide-field autofluorescence using Optos' ultra-widefield retina imaging, 76% had abnormalities in the peripheral...

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Dry Macular Degeneration
Aug 26, 2010
Some patients with geographic atrophy benefit for at least 3 years from an autologous graft of choroid and retinal pigment epithelium (RPE), according to a new research study. Geographic atrophy accounts for severe vision loss and blindness in about 40% of the patients with age-related macular degeneration (AMD). Therapeutic approaches are...

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Torpedo maculopathy
Mar 28, 2010
Torpedo maculopathy is a benign, congenital defect of the retinal pigment epithelium. This study was a retrospective, observational case series. The medical records of 13 patients, age 1–68 years, seen between 1982 and 2009 were reviewed. Patients were evaluated for lesion features and course on follow-up, visual acuity, fluorescein...

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Dry Macular Degeneration
Dec 23, 2009
Selective retinal pigment epithelial photocoagulation of the margins of geographic atrophy does not slow the progression of the disease, according to a new study. Geographic atrophy is the end stage of dry age-related macular degeneration (AMD). Geographic atrophy has been shown to enlarge gradually over time. Studies using fundus...

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Stratus OCT Instrument
Sep 18, 2009
A new study that compares images obtained with high-resolution spectral-domain optical coherence tomography (OCT) to those with fundus autofluorescence (FAF) imaging in patients with geographic atrophy finds that severe alterations of the outer retinal layers on spectral-domain OCT correspond significantly to increased autofluorescence....

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Dry Macular Degeneration
Sep 17, 2009
A new report from the AREDS study group finds that the onset of central GA after the diagnosis of any GA was 2.5 years. Geographic atrophy (GA) represents the end-stage of dry age-related macular degeneration (AMD). Despite the recent breakthrough by anti–VEGF therapy for the active neovascular form, there is still no proven treatment to...

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fundus autofluorescence
Aug 16, 2009
A study correlates fundus autofluorescence (FAF) and optical coherence tomography (OCT) with visual acuity (VA) in patients with cystoid macular edema (CME) secondary to uveitis. Lipofuscin is a pigment in the retinal pigment epithelium that will fluoresce when excited by ultraviolet or blue light. Examination using UV or blue light reveals...

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Dry Macular Degeneration
Aug 12, 2009
A study of patients with foveal sparing geographic atrophy (GA) employing a novel combination of spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy (cSLO) finds that thickening of the fovea may reflect a pre-apoptotic stage of neuronal cellular elements indicating imminent atrophy. Geographic...

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fundus autofluorescence
Jun 18, 2009
A study of fundus autofluorescence (FAF) characteristics of choroidal neovascularisation (CNV) secondary to pathological myopia (PM) has a specific FAF pattern. This study was an open-label, prospective, interventional case series of 42 patients affected by subfoveal CNV in PM underwent PDT with a 24-month follow-up. Each patient underwent an...

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Central serous chorioretinopathy
Jan 20, 2009
Autofluorescence imaging is able to can detect recent episodes of central serous chorioretinopathy (CSCR), and may be useful in the differenial diagnosis and monitoring of patients with the disorder, according to a new study. Fundus autofluorescence is a technique of visualizing macular pigment that utilizes the pigment's natual fluorescence...

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