MyVisionTest News Archive

Displaying news items tagged with vitreous (More tags »)
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Submacular hemorrhage
Oct 10, 2010
This review summarises what is known about submacular hemorrhage (SMH) in neovascular age-related macular degeneration (nAMD) and discusses a variety of therapeutic interventions. The exact incidence of SMH in patients with nAMD is unknown, and risk factors for its occurrence ill defined. It is known, however, to be a relatively common problem...

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Vitreomacular traction
Sep 12, 2010
Good visual outcomes can be achieved without surgery in patients with choroidal neovascularization (CNVM) that develop vitreomacular traction (VMT), according to a new study. Adhesion between the retina and vitreous occurs regularly in patients with age-related macular degeneration (AMD) and may cause VMT in eyes with CNVM, a retrospective...

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Vitreous
Aug 29, 2010
Vitrectomy decreases the progression of age-related macular degeneration (AMD), according to a new research study. There is no published evidence that a vitrectomy hastens the progression of AMD. Intraocular surgery is known however to incite significant inflammation and breakdown of the blood–ocular barrier, which may last from weeks to...

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Vitreomacular traction
Jul 19, 2010
A series of patients with acute and transient presentation of vitreomacular traction following routine cataract surgery is presented. A syndrome of acute vitreomacular traction following uneventful cataract surgery has been described in the literature. Evidence of vitreomacular traction following cataract surgery can be detected using optical...

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Vitreomacular traction
Jun 27, 2010
ThromboGenics' phase 3 trial evaluating microplasmin for the non-surgical treatment of focal vitreomacular adhesion has met its primary endpoint of resolving vitreomacular adhesion at 1 month, the company announced in a press release. "The ability to cure a significant proportion of patients with a range of retinal disorders, including...

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Vitrectomy
Feb 21, 2010
Intravitreal Avastin (bevacizumab, IVB) injection as an adjunct to vitrectomy in the management of severe proliferative diabetic retinopathy (PDR) improves the anatomical and functional outcomes of surgery, according to a new study. Diabetic retinopathy is the result of microvascular retinal changes. Hyperglycemia-induced pericyte death and...

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Laboratory mouse
Dec 14, 2009
Intravitreal microplasmin degrades fibronectin and laminin, two major extracellular matrix glycoproteins, at the vitreoretinal junction as well as at the outer retina, according to a new study performed on laboratory rats. Vitreoretinal interaction has been implicated as possibly contributing to the onset of macular degeneration. Furthermore,...

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Vitreous
Oct 21, 2009
An intravitreal injection of microplasmin may aid in releasing the posterior vitreous from the retinal surface in patients with diabetic macular edema and may yield complete posterior vitreous detachment in some patients, according to a study. Microplasmin (ThromboGenics), a recombinant product, contains plasmin’s catalytic domain and shares...

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Vitreomacular traction
Jul 22, 2009
ThromboGenics announces that microplasmin, which is in Phase III trials for the treatment of vitreomacular adhesion, is progressing according to schedule. Microplasmin's Phase III program is referred to as the MIVI-TRUST (Microplasmin for IntraVitreous Injection-Traction Release without Surgical Treatment) program. This program involves two...

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Vitreous
Jul 22, 2009
An experimental drug called microplasmin is being studied as a treatment for focal vitreomacular adhesion. Traction at the vitreomacular interface is a major contributor to macular dysfunction. Fluid shifts generated by eye movement exert tractional forces on the fovea that can lead to the development or progression of macular holes or cystoid...

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