MyVisionTest News Archive

Displaying news items tagged with retinal degeneration (More tags »)
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Laboratory glassware
Oct 25, 2010
The mammalian target of rapamycin (mTOR) pathway plays a role in regulating age-related changes in human retinal pigment epithelial (RPE) cells, and inhibition of mTOR could delay the aging process of the RPE, according to a new study. Age-dependent degeneration of the RPE is a hallmark pathologic change of AMD, especially in the atrophic form....

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Liposome
Aug 27, 2010
Researchers demonstrate that non-viral gene therapy can delay the onset of some forms of retinal degeneration and preserve vision, according to a new study. The researchers developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. "Our work shows that...

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Myopic macular degeneration
Aug 25, 2010
A new study finds that myopic maculopathy tends to progress in approximately 40% of highly myopic eyes, and the pattern of progression affects the visual prognosis. It is suggested that preventive therapy targeting posterior staphyloma should be considered to prevent the visual impairment caused by the progression of myopic maculopathy....

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Obesity
Jul 28, 2009
A novel strain of laboratory rats that develop both obesity and retinal degeneration is studied to gain an understanding as to why obesity is association with a higher risk for macular degeration. A strong association between macular degeneration and obesity has been shown in humans. A recently published risk calculator, based upon data from...

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Laboratory mouse
Apr 21, 2009
Age-related iron accumulation within the retinal pigment epithelium (RPE) may increase oxidative stress and contribute to the development of age-related macular degeneration (AMD), according to a newly published study. Increasing evidence shows oxidative stress and free radical damage in the RPE may underlie the pathogenesis of AMD. The RPE...

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Laboratory mouse
Apr 16, 2009
A new study finds that the growth factor known as TGF-beta is required by retinal blood vessels and that blocking it can cause retinal dysfunction. Capillaries are the smallest blood vessels in the body and the site at which oxygen and nutrients are transferred from the blood to the tissues. A capillary is composed of an endothelial cell,...

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Age-related Macular Degeneration
Jan 19, 2009
Retinal pigmented epithelium (RPE) transplantation has been assessed as a potential technique to preserve the visual function in persons with age-related macular degeneration (AMD). However, RPE survival following transplantation is limited, in part, because of lack of attachment of the transplanted cells to Bruch's membrane. Integrins are a...

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Laboratory mouse
Jan 13, 2009
Researchers working with mice have identified a protein that appears to prolong the lives of retinal cells in both healthy and diseased eyes. The protein, known as histone deacetylase 4 (HDAC4), is naturally produced by both mice and humans and is also involved in the regulation of bone and muscle development. The researchers discovered that...

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