Interferon γ–inducible protein-10 (IP-10) and eotaxin may be early biomarkers in age-related macular degeneration (AMD), according to a new study. Chronic inflammation consists of a series of biological responses to harmful stimuli that include activation of subsets of immune cells, which are recruited to inflamed areas, angiogenesis and...

A research study using laboratory rats has identified the eosinophil/mast cell chemokine receptor CCR3 as a new biologic marker for choroidal neovascularization (CNV) that has strong potential as a new target for therapeutic intervention. CCR3 is a receptor found on the surface of a variety of cells, including white blood cells, for a chemical...