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DNA double-helix molecule
Feb 27, 2012
A new study finds that genes in different pathways influence progression to different stages of age-related macular degeneration (AMD). AMD is known to be influenced primarily by genetic factors, although environmental and behavioral factors also play important roles. Multiple studies have shown that several genes in the alternative complement...

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Calculator
Feb 26, 2012
When patients are told by their ophthalmologist that they have early signs of age-related macular degeneration (AMD), they often ask about the risk of their AMD progressing. Long-term epidemiological studies that have collected information on the prevalence, incidence, and natural history of AMD provide data to answer this question. These studies...

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Dry Macular Degeneration
Feb 26, 2012
Researchers have developed a risk score for developing geographic atrophy (GA) involving easily obtainable information among patients with bilateral large drusen. Choroidal neovascularization (CNV) and geographic atrophy (GA) are two forms of end-stage AMD. GA is responsible for about 10% of the severe vision loss attributed to the AMD, and...

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Calculator
Feb 26, 2012
Researchers have designed a new risk assessment model for development of advanced age-related macular degeneration (AMD) incorporating phenotypic, demographic, environmental, and genetic risk factors. As progress in designing better preventive measures and earlier treatment options accelerates and new gene associations are identified that add...

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Double helix DNA
Feb 24, 2012
AMD has been one of the success stories of the genome revolution and is probably one of the best characterized of the complex trait diseases in terms of genetic predisposition. Besides age, genetic background is the most significant non-modifiable risk factor for all stages of AMD, while smoking is the most significant modifiable risk factor....

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Central serous chorioretinopathy
Mar 7, 2011
The authors report on a patient with CSCR that developed subretinal fibrosis that responded favorably to treatment with intravitral Lucentis (ranibizumab). Central serous chorioretinopathy (CSCR) manifests as detachment of the macula and can be attributed to focal or multifocal leakage in the retinal pigment epithelium (RPE). Increased...

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Avastin
Feb 15, 2011
Small lesion size and worse pre-treatment vision were associated with improved visual outcome 24 months after intravitreal Avastin (bevacizumab, IVB) treatment for myopic choroidal neovascularization (mCNV). Extreme myopia may result in degenerative changes of the retina. These degenerative changes may lead to complications such as retinal...

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Eggs
Jan 22, 2011
Macular pigment is the collective name for three carotenoids, lutein, zeaxanthin and meso-zeaxanthin, which are found at higher concentrations in the retina than anywhere else in the body, and to the exclusion of all other carotenoids. They are only accessible to the body by dietary intake of foodstuffs or supplements containing them, with high...

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Avastin
Jan 21, 2011
The presence of cystoid macular edema (CME) and thicker subretinal tissue (SRT) on fluorescein angiography (FA) and optical coherence tomography (OCT) are characteristics predicting poor responses to intravitreal Avastin (bevacizumab) therapy in patients with neovascular age-related macular degeneration (AMD), according to a new study. In the...

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Age-related macular degeneration
Oct 21, 2010
Paperwork delays in getting approval for Lucentis (ranibizumab) therapy of neovascular age-related macular degeneration (AMD) in Germany can lead to vision loss, according to a new study. In Germany, Lucentis treatment is usually covered by the public health insurance only after reviewing each individual case. In addition, health insurance...

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