MyVisionTest News Archive

Displaying news items tagged with microplasmin (More tags »)
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Vitreomacular traction
Jun 27, 2010
ThromboGenics' phase 3 trial evaluating microplasmin for the non-surgical treatment of focal vitreomacular adhesion has met its primary endpoint of resolving vitreomacular adhesion at 1 month, the company announced in a press release. "The ability to cure a significant proportion of patients with a range of retinal disorders, including...

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Laboratory mouse
Dec 14, 2009
Intravitreal microplasmin degrades fibronectin and laminin, two major extracellular matrix glycoproteins, at the vitreoretinal junction as well as at the outer retina, according to a new study performed on laboratory rats. Vitreoretinal interaction has been implicated as possibly contributing to the onset of macular degeneration. Furthermore,...

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Vitreous
Oct 21, 2009
An intravitreal injection of microplasmin may aid in releasing the posterior vitreous from the retinal surface in patients with diabetic macular edema and may yield complete posterior vitreous detachment in some patients, according to a study. Microplasmin (ThromboGenics), a recombinant product, contains plasmin’s catalytic domain and shares...

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Vitreomacular traction
Jul 22, 2009
ThromboGenics announces that microplasmin, which is in Phase III trials for the treatment of vitreomacular adhesion, is progressing according to schedule. Microplasmin's Phase III program is referred to as the MIVI-TRUST (Microplasmin for IntraVitreous Injection-Traction Release without Surgical Treatment) program. This program involves two...

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Vitreous
Jul 22, 2009
An experimental drug called microplasmin is being studied as a treatment for focal vitreomacular adhesion. Traction at the vitreomacular interface is a major contributor to macular dysfunction. Fluid shifts generated by eye movement exert tractional forces on the fovea that can lead to the development or progression of macular holes or cystoid...

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