Cardiovascular risk factors such as smoking, hypertension, and atherosclerosis seem to play an important role in the development of choroidal neovascularization (CNV). Several cross-sectional studies have provided evidence suggesting that choroidal and retinal blood flow is decreased in AMD. The presence of abnormal choroidal circulation...

Today's aging baby boomers might be less likely to have age-related macular degeneration (AMD) than their forebears, according to a new study presented at the Association for Research in Vision and Ophthalmology 2010 Annual Meeting. "This rapid decline in age-related macular degeneration, which was 68% lower for each generation, suggests that...

A mathematical model has been developed to predict the absolute risk of geographic atrophy and neovascular age-related macular degeneration (AMD) risk based on smoking history and genetic risk factors in individuals of European ancestry. Although AMD was long thought to have primarily an environmental etiology, genetic variation is now known...

Anticoagulants and antiplatelet agents are strongly associated with the development of large subretinal hemorrhages in age-related macular degeneration (AMD) patients, according to a new study. Patients with thick submacular hemorrhage complicating AMD typically have a poor visual prognosis. According to retrospective reports, the natural...

In the EUREYE study, a positive association between diabetes mellitus and neovascular age-related macular degeneration (AMD) was found. Other than age, the epidemiologic risk factors most consistently associated with AMD are cardiovascular risk factors. Many cardiovascular disease risk factors have been suggested as potential risk factors for...