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DNA double-helix molecule
Feb 27, 2012
A new study finds that genes in different pathways influence progression to different stages of age-related macular degeneration (AMD). AMD is known to be influenced primarily by genetic factors, although environmental and behavioral factors also play important roles. Multiple studies have shown that several genes in the alternative complement...

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Calculator
Feb 26, 2012
When patients are told by their ophthalmologist that they have early signs of age-related macular degeneration (AMD), they often ask about the risk of their AMD progressing. Long-term epidemiological studies that have collected information on the prevalence, incidence, and natural history of AMD provide data to answer this question. These studies...

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Dry Macular Degeneration
Feb 26, 2012
Researchers have developed a risk score for developing geographic atrophy (GA) involving easily obtainable information among patients with bilateral large drusen. Choroidal neovascularization (CNV) and geographic atrophy (GA) are two forms of end-stage AMD. GA is responsible for about 10% of the severe vision loss attributed to the AMD, and...

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Calculator
Feb 26, 2012
Researchers have designed a new risk assessment model for development of advanced age-related macular degeneration (AMD) incorporating phenotypic, demographic, environmental, and genetic risk factors. As progress in designing better preventive measures and earlier treatment options accelerates and new gene associations are identified that add...

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Double helix DNA
Feb 24, 2012
AMD has been one of the success stories of the genome revolution and is probably one of the best characterized of the complex trait diseases in terms of genetic predisposition. Besides age, genetic background is the most significant non-modifiable risk factor for all stages of AMD, while smoking is the most significant modifiable risk factor....

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Racial groups
Jan 16, 2012
Age-related Macular Degeneration (AMD) has long been thought to be more frequent in non-Hispanic whites than in blacks in the United States. This was based on observations reported in clinical case series. The use of new AMD classification schemes and severity scales in large population-based studies has confirmed that non-Hispanic whites have...

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Age-related Macular Degeneration
Jan 16, 2012
The Latino Eye Study found that ocular factors such as cataract, cataract surgery, and refractive errors associated with early age-related macular degeneration (AMD) lesions found in Latinos are consistent with those in non-Hispanic Whites. Previous population-based studies among Caucasians have identified possible associations of various...

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Central Serous Chorioretinopathy
Mar 28, 2011
A history of psychiatric illness is associated with an increased risk of recurrence of serous macular detachment in untreated patients with central serous chorioretinopathy (CSC), according to a new study. Retrospective review of untreated CSC patients with a follow-up of ≥3 years. Patient demographics, visual outcome and risk factors for...

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cardiovascular system
Mar 10, 2011
Patients with elevated concentration of plasma lipoproteins and C-reactive protein (CRP) have a higher risk of developing AMD, according to a new study. Cardiovascular disease and AMD have been shown to share some of the same risk factors, including high body mass index (BMI), C-reactive protein, other cytokines, and history of smoking....

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Cigarette
Jan 11, 2011
Modifying lifestyle behaviors of diet, smoking, and physical activity may reduce the risk of age-related macular degeneration (AMD) as much as 3-fold, according to a new study. The population included 1313 participants (aged 55-74 years) in the Carotenoids in Age-Related Eye Disease Study, an ancillary study of the Women's Health Initiative...

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