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Age-related macular degeneration
Feb 27, 2011
Combined treatment of reduced-fluence verteporfin photodynamic therapy (PDT), intravitreal Lucentis (ranibizumab), intravitreal dexamethasone and oral minocycline for choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) was not more effective than combination therapy with standard-fluence PDT plus Lucentis,...

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Retinal angiomatous proliferation
Feb 26, 2011
Intravitreal Lucentis (ranibizumab) combined with photodynamic therapy (PDT) yielded anatomical and functional improvement in eyes with retinal angiomatous proliferation (RAP) with serous pigment epithelial detachment, a study said. The prospective pilot study included 10 eyes of nine newly diagnosed patients, of which nine eyes of eight...

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Laser eye surgery
Oct 25, 2010
A combination of photodynamic therapy (PDT) plus intravitreal Lucentis (ranibizumab) can achieve visual results in patients with choroidal neovascularization secondary to age-related macular degeneration (AMD) similar to those of Lucentis monotherapy with fewer retreatments, according to a new study. Despite success in treating leakage from new...

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Visudyne
Oct 14, 2010
Triple therapy with intravitreal Avastin (bevacizumab) or Lucentis (ranibizumab), dexamethasone and verteporfin photodynamic therapy (PDT) for exudative age-related macular degeneration (AMD) results in fewer retreatments than either Avastin or Lucentis alone, according to a new study. No single therapy completely addresses all of the ways...

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Diabetes
Sep 20, 2010
Two-year results from a phase 2 trial suggest that anti-VEGF therapy reduces retinal thickness and significantly improves visual acuity in patients with diabetic retinopathy. Combination therapy with laser may reduce the number of injections required, as well as further reducing foveal thickness, Dean Eliott, MD, said at the American Society of...

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Lucentis
Jul 24, 2010
The addition of standard-fluence verteporfin photodynamic therapy (PDT) delivered on the first day to a Lucentis (ranibizumab) regimen for choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) does not improve outcomes at 1 year of follow-up compared with Lucentis monotherapy, according to a new study. Despite...

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Macular degeneration
Jun 27, 2010
Combination therapies generated greater visual acuity gains with fewer reinjections compared with monotherapy in a phase 2 study of patients with exudative age-related macular degeneration. In the phase 2 RADICAL (Reduced fluence Visudyne anti-VEGF-dexamethasone in combination for AMD lesions) study, mean gain in visual acuity from baseline in 3...

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Polypoidal choroidal vasculopathy
Jun 17, 2010
Combined verteporfin photodynamic therapy (PDT) and Lucentis (ranibizumab) shows promising results for the treatment of polypoidal choroidal vasculopathy (PCV). Polypoidal choroidal vasculopathy (PCV) is a condition characterized by multiple, recurrent, serosanguinous pigment epithelial detachment (PED), and neurosensory retinal detachment due...

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Drusenoid pigment epithelial detachment
May 9, 2010
Intravitreal injection of an anti-VEGF agent and a complement inhibitor proved safe in treating age-related macular degeneration, Dr Scott Cousins, said at the Association for Research in Vision and Ophthalmology 2010 meeting. "Drusen contain all the different complement family of molecules, not just the effectors but also the activator and...

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Age-related macular degeneration
May 8, 2010
Intravitreal Avastin (bevacizumab, IVB) combined with intravitreal triamcinolone acetonide (steroid, IVTA) may provide temporary improvement of exudative age-related macular degeneration (AMD) after unsuccessful Avastin monotherapy, according to a recent research report. No single therapy completely addresses all of the ways that neovascular...

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