MyVisionTest News Archive

Displaying news items tagged with CNV (More tags »)
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Intravitreal injection
Nov 26, 2009
The vision of patients with persistent or reactivated choroidal neovascularization (CNV) that had been previously treated with photodynamic therapy (PDT) improve less than treatment-naive patients. Baseline assessments including best-corrected visual acuity, fluorescein angiography (FFA), and optical coherent tomography (OCT) were performed....

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Uveitis
Nov 18, 2009
Avastin (bevacizumab) is effective in the treatment of choroidal neovascularization (CNV) and cystoid macular edema (CME) secondary to inflammatory eye disease, according to a new research study. Choroidal neovascularization (CNV) and cystoid macular edema (CME) are well-recognized complications of inflammatory eye disease and important causes...

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Laboratory mouse
Nov 17, 2009
In a study on laboratory rats, orally administrated doxycycline, an inexpensive and widely used broad-spectrum antibiotic, was found to reach the choroid and effectively hampered the progression of experimental choroidal neovascularization. Doxycycline is a member of the tetracycline antibiotics group that is clinically useful because of its...

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Choroidal neovascularization
Oct 21, 2009
A new study examining the relationship between the choriocapillaris (CC) and retinal pigment epithelial changes in age-related macular degeneration (AMD) finds that the primary insult in geographic atrophy (GA) appears to be at the level of the retinal pigment epithelium (RPE), where retinal pigment epithelial atrophy preceeds secondary...

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Eye surgery
Oct 16, 2009
The creation of a full-thickness autologous patch (FTAP) for choroidal neovascularization through a 180° peripheral retinotomy is feasible and safe. This retrospective study evaluated the feasibility of transplanting a full-thickness patch of choroid, choriocapillaries, Bruch’s membrane and RPE (RPE-choroid FTAP) from the peripheral to the...

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Tags: surgery, CNV

Angioid streaks
Oct 15, 2009
A case report of worsening of angoid streaks in a patient following tresatment of associated choroidal neovascularization (CNV) with Avastin (bevacizumab) is presented. Angioid streaks are cracks in Bruch's membrane (the membrane that seperates the retina from the choroid), and are seen in association with a variety of systemic medical...

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Monkey
Oct 15, 2009
Intravitreal JSM6427, a potent and selective inhibitor of integrin α5β1, provided dose-dependent inhibition of choroidal neovascularization (CNV) in monkey and rabbit experimental models; suggesting that JSM6427 may provide a new approach for the treatment of ocular neovascular diseases such as age-related macular degeneration (AMD) in...

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Uveitis
Sep 14, 2009
A prospective case series finds that systemic steroids in combination with mycophenolate mofetil is a promising therapy for the control of parafoveal uveitic choroidal neovascularization (CNV) unresponsive to the traditional immunosuppressive agents. Mycophenolic acid or mycophenolate is an immunosuppressant drug used to prevent rejection in...

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Laboratory mouse
Aug 12, 2009
A study involving mice finds that lectin-like oxidized low-density lipoprotein receptor type 1 (LOX-1) is involved in the formation of choroidal neovascularization (CNV) and might thus be a novel therapeutic target for patients with neovascular age-related macular degeneration (AMD). Recently, similarities have been suggested between the...

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Laboratory mouse
Jul 28, 2009
Using a synthetic form of complement factor H (fH), called CR2-fH, researchers were able to inhibit development of choroidal neovascularization (CNV) in a mouse model of age-related macular degeneration (AMD). Studies on the pathogenesis of AMD indicate that inflammation is a fundamental component of the disease process and that the alternative...

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