MyVisionTest News Archive

Displaying news items tagged with adverse drug effects (More tags »)
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Uveitis
Feb 27, 2011
Intravitreal injections with anti-VEGF agents such as Avastin (bevacizumab) and Lucentis (ranibizumab) have been increasingly used for the treatment of retinal disorders over the past years. Although both drugs are often repeatedly injected in patients with choroidal neovascularizations, serious adverse events are rare. Here, is presented a case...

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cardiovascular system
Feb 27, 2011
There is evidence of increased risk of stroke and hemorrhage associated with intravitral Lucentis (ranibizumab) therapy of age-related macular degeneration (AMD), and insufficient evidence of Avastin (bevacizumab) safety, according to a major review of the literature. In some patients treated with systemic anti–VEGF-A agents, inhibition of...

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Intravitreal injection
Feb 26, 2011
The judicious use of anti-VEGF agents for the treatment of age-related macular degeneration (AMD) is reasonable, considering the biological and clinical responses, a speaker said at Macula 2011 meeting. Anti-VEGF injections can be associated with elevated IOP, tachyphylaxis (drug resistance) and reduced ocular perfusion, Elias Reichel, MD, said...

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Retinal detachment
Jan 20, 2011
To determine the incidence of rhegmatogenous retinal detachments (RD) after intravitreal injection in six high-volume centres. The risk of serious adverse events reported after intravitreal (IVT) injection injection is low. Endophthalmitis, which is infection inside the eye, is perhaps the most serious complication of IVT injection....

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Intravitreal injection
Jan 11, 2011
Prophylactic use of intraocular pressure (IOP)-lowering medication is ineffective in reducing the IOP spikes that often occur after intravitreal injections of Macugen (pegaptanib), Avastin (bevacizumab), and Lucentis (ranibizumab), according to a recent study. Seventy-one patients with exudative age-related macular degeneration received...

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Intravitreal injection
Nov 15, 2010
Streptococcus is isolated much more frequently from endophthalmitis cultures after intravitreal injection (IVI) of antivascular endothelial growth-factor (anti-VEGF) agents than after ocular surgery, results of a meta-analysis show. The new research was presented at the American Academy of Ophthalmology 2010 Annual Meeting. Ophthalmologists...

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Intravitreal injection
Oct 24, 2010
Avastin (bevacizumab) and Lucentis (ranibizumab) use was not associated with increased risks of mortality, myocardial infarction, bleeding, or stroke compared with photodynamic therapy or Macugen (pegaptanib) use. Before June 2006, the approved pharmacologic therapies for neovascular age-related macular degeneration (AMD) in the United States...

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Laboratory glassware
Sep 21, 2010
VEGF antagonists, such as Avastin (bevacizumab) and Lucentis (ranibizumab), impair the barrier function of cultured retinal pigment epithelium (RPE) cells, according to a new study. In spite of the favorable results of anti-VEGF therapies in the treatment of exudative age-related macular degeneration (AMD), several adverse incidents are related...

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retinal nerve fiber layer
Aug 25, 2010
Long-term intravitreal injection of anti–vascular endothelial growth factor (VEGF) agents does not adversely affect on the thickness of the retinal nerve fiber layer (RNFL) in patients with wet age-related macular degeneration (AMD). The use of intravitreal anti-VEGF agents has become the standard of care for patients with AMD. The duration...

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Avastin
Jun 27, 2010
Intravitreal injection of Avastin (bevacizumab) is associated with a low but significant risk of acute intraocular inflammation and may result in significant visual loss, according to a new study. Acute intraocular inflammation is a well recognized and potentially severe complication of intravitreal Avastin (bevacizumab). In previous reports...

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