MyVisionTest News Archive

Displaying news items tagged with CNV (More tags »)
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Laboratory glassware
Jul 18, 2009
A new study from Saudi Arabia finds that YC-1, an inhibitor of hypoxia-inducible factor (HIF), has antiangiogenic properties that make it a potentially valuable therapeutic agent in the treatment of age-related macular degneration (AMD). The HIF signaling cascade plays a critical role in angiogenesis by activating the transcription of genes...

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fundus autofluorescence
Jun 18, 2009
A study of fundus autofluorescence (FAF) characteristics of choroidal neovascularisation (CNV) secondary to pathological myopia (PM) has a specific FAF pattern. This study was an open-label, prospective, interventional case series of 42 patients affected by subfoveal CNV in PM underwent PDT with a 24-month follow-up. Each patient underwent an...

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CCR3 receptor
Jun 16, 2009
A research study using laboratory rats has identified the eosinophil/mast cell chemokine receptor CCR3 as a new biologic marker for choroidal neovascularization (CNV) that has strong potential as a new target for therapeutic intervention. CCR3 is a receptor found on the surface of a variety of cells, including white blood cells, for a chemical...

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cardiovascular system
Jun 16, 2009
A new study finds evidence of systemic complement activation in patients with recent onset exudative age-related macular degeneration (AMD). It is belived that chronic inflammatory processes play a role in the progression of AMD. The complement system plays an important role in modulating the inflammatory response. Activation of the complement...

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Laboratory mouse
Jun 15, 2009
A new study finds that octreotide, a synthetic form of somatostatin (growth hormone inhibiting hormone), is able to inhibit choroidal neovascularization in rats. Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation. Somatostatin is produced by numerous organs throughout the...

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Myopic macular degeneration
Jun 15, 2009
A new study finds that intravitreal Lucentis (ranibizumab) is effective for the primary treatment of myopic choroidal neovascularization (mCNV). Extreme myopia may result in degenerative changes of the retina. These degenerative changes may lead to complications such as retinal detachment or macular degeneration. Degenerative changes affecting...

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Cataract surgery
Jun 15, 2009
A study of patients undergoing submacular surgery for choroidal neovascularization (CNV) finds that very large, predominantly hemorrhagic subfoveal neovascular AMD lesions were associated with higher risk of development of rhegmatogenous retinal detachment (RRD). The Submacular Surgery Trials investigated the outcome following surgical removal...

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Laboratory mouse
May 22, 2009
New information on the anti-angiogenic action of TM601 was presented at the 2009 Association for Research in Vision and Ophthalmology Annual Meeting. According to the poster, TM601 binding co-localizes with annexin A2 on the surface of activated vascular endothelial cells in choroidal neovascularization (CNV) lesions, induces apoptosis and causes...

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Lacquer cracks in pathologic myopia
May 21, 2009
A new study finds that intravitreal injection of Avastin (bevacizumab) in eyes with mCNV can improve visual acuity (VA) and macular sensitivity as measured by microperimetry for at least 6 months. However, some patients showed scotoma enlargement after treatment was initiated. Myopic choroidal neovascularization (mCNV) is one of the most...

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Cirrus High Definition OCT
Apr 24, 2009
A spectral domain optical coherence tomography (SDOCT) study of the response of neovascular age-related macular degeneration (AMD) to Lucentis (ranibizumab) therapy reveals that the size of the RPE lesion may be more relevant for visual function than retinal thickness. The suggested Lucentis monthly retreatment regimen represents a substantial...

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