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Diabetes
Aug 26, 2010
Systematic review and meta-analysis of the treatment of diabetic macular edema (DME) with intravitreal Avastin (bevacizumab, IVB) finds that IVB is an effective short-term treatment for diabetic macular edema, and that its efficacy wanes after 6 weeks. Diabetic retinopathy is the result of microvascular retinal changes. Hyperglycemia-induced...

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Intravitreal injection
Aug 24, 2010
Intravitreal injections performed with a 30-gauge needle more often result in significant elevations of intraocular pressure (IOP) requiring extraction of fluid from the anterior chamber of the eye to rapidly lower the pressure, a procedure known as paracentesis, than when injections are performed using a 27-guage needle. Elevation of IOP is a...

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idiopathic macular telangiectasia
Aug 20, 2010
Intravitreal Avastin (bevacizumab) fails to improve vision in eyes with idiopathic macular telangiectasia (IMT). Idiopathic macular telangiectasia (IMT) are dilated retinal capillaries that develop without a known cause. The capillaries leak into the retina and can cause cystoid macular edema. There are 2 types of macular telangiectasia....

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Polypoidal choroidal vasculopathy
Aug 20, 2010
Intravitreal Avastin (bevacizumab, IVB) maintains visual acuity of patients with polypoidal choroidal vasculopathy (PCV) after 1 year of follow-up, according to a new study. Polypoidal choroidal vasculopathy (PCV) is a condition characterized by multiple, recurrent, serosanguinous pigment epithelial detachment (PED), and neurosensory retinal...

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Intraocular pressure
Aug 19, 2010
A retrospective record review finds that 6% of patients undergoing repeated intravitreal injections of antivascular endothelial growth factor (VEGF) agents develop sustained elevation of intraocular pressure (IOP) Elevation of IOP is a risk factor for glaucoma. IOP reflects a balance between the rate that fluid flows into the eye and the rate...

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Branch retinal vein occlusion
Aug 19, 2010
Avastin (bevacizumab, IVB) accelerates recovery from macular edema following branch retinal vein occlusion (BRVO), but do not have any significant effects on visual acuity after 12 weeks. Retinal vein occlusion is a common cause of sudden vision loss in adults. Central retinal vein occlusion occurs when the main vein draining blood from the eye...

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Polypoidal choroidal vasculopathy
Jul 29, 2010
Outcomes following photodynamic therapy (PDT) combined with intravitreal Avastin (bevacizumab) injection were superior to PDT monotherapy in patients with polypoidal choroidal vasculopathy (PCV), according to a new study. Polypoidal chodoridal vasculopathy (PCV) is characterized by a complex of branching vascular networks terminating in...

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Avastin
Jul 29, 2010
After 24 months of follow-up, patients treated with intravitreal Avastin (bevacizumab, IVB) have superior outcomes compared to patients treated with photodynamic therapy (PDT) for myopic choroidal neovascularisation (mCNV), according to a new study. Extreme myopia may result in degenerative changes of the retina. These degenerative changes may...

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Avastin
Jun 27, 2010
Intravitreal injection of Avastin (bevacizumab) is associated with a low but significant risk of acute intraocular inflammation and may result in significant visual loss, according to a new study. Acute intraocular inflammation is a well recognized and potentially severe complication of intravitreal Avastin (bevacizumab). In previous reports...

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Pigment epithelial detachment
Jun 17, 2010
In patients with age-related macular degeneration (AMD) and pigment epithelial detachment (PED) secondary to occult choroidal neovascularization (CNV), Avastin (bevacizumab) therapy decreased PED height but this does not necessarily correlate with improvment in visual acuity (VA), according to a new study. A PED occurs when fluid enters the...

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