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Displaying news items tagged with genetics (More tags »)
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DNA double-helix molecule
Jul 23, 2008
ArcticDx Inc has completed a licence agreement with Cambridge Enterprise Limited for a single nucleotide polymorphism (SNP) located in the complement C3 gene that is a demonstrated predictive indicator for the genetic diagnosis of age-related macular degeneration, one of the commonest causes of blindness in Europe and the USA. ArcticDx Inc...

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Tags: AMD, genetics

Age-related Macular Degeneration
Jul 5, 2008
Siblings of age-related macular degeneration (AMD) patients are at a 14 times greater risk of developing AMD than controls and 54 times as likely to develop choroidal neovascularization, a study showed. "Age and smoking are known to be significant risk factors for AMD, and if we do an adjusted logistic regression analysis to account for these...

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Tags: AMD, genetics

DNA double-helix molecule
Jun 18, 2008
A new study links variations within the HTRA1 gene with exudative AMD. There has been some controversy surrounding the HTRA1 gene and AMD. Apparently, there are several very closely related genetic variants on chomosome 10q26 that makes determination of the various contributions of each very difficult. This study was conducted to identify...

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Diagram of a mitochondria
May 7, 2008
A new study provides evidence that variation in the mitochondrial genome contributes to susceptibility to AMD. The magnitude of the association suggests that it may be an important new risk factor for the development of AMD. Mitochondria are located within all cells and play a central role in cellular energy production, free radical production,...

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Tags: genetics, AMD

May 5, 2008
Genetic studies of age-related maculopathy (ARM), including family-based linkage studies and case-control association studies, have yielded valuable insights into the risks of developing this condition and potential disease-causing mechanisms. Variants in the complement factor H gene and LOC387715 have been shown to be major risk factors for ARM....

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Tags: AMD, genetics

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