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Displaying news items tagged with clinical trial (More tags »)
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Eye Drops
Apr 17, 2009
SARcode Corporation announced today the results of its Phase 1 trial of the safety, tolerability, and pharmacokinetics of SAR 1118 Ophthalmic Solution in healthy volunteers. SAR 1118 was well-tolerated and demonstrated a favorable safety profile when administered by topical ocular instillation. SAR 1118 is a potent novel small molecule...

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Dry macular degeneration
Apr 16, 2009
Sirion Therapeutics announced positive results from an interim analysis of its Phase II trial evaluating fenretinide for the treatment of geographic atrophy (GA). This interim analysis was triggered when all patients had reached the 12 month visit. Fenretinide is an oral vitamin A binding protein antagonist being studied in patients with...

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AREDS
Jan 19, 2009
The Age-Related Eye Disease Study (AREDS) released 10-year follow-up data showing that baseline AMD score, smoking, age and AREDS supplementary treatment are predictors for 10-year progression rates, according to a presentation at the Retina Subspecialty Day preceding the American Academy of Ophthalmology meeting. The study of 4,757 patients...

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Lucentis
Jan 15, 2009
The 2-year results of the ANCHOR clinical trial finds that Lucentis therapy for age-related macular degeneration (AMD) with new-onset, predominantly classic choroidal neovascularization (CNV) is superior to verteporfin photodynamic therapy (PDT). The ANCHOR study is a 2-year, phase III clinical trial that compared Lucentis (ranibizumab) with...

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Age-related macular degeneration
Dec 17, 2008
OPKO Health, Inc. has announced that it has completed enrollment in the company's Phase III clinical trial of bevasiranib for the treatment of wet age-related macular degeneration (AMD). The multi-national study has enrolled more than 330 patients and is designed to assess the efficacy and safety of bevasiranib administered every 8 or 12...

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The Iluvien insert, shown on a human finger to indicate size
Dec 17, 2008
pSivida Corp has announced that a clinical trial has begun using its Medidur delivery technology to treat geographic atrophy, the end-stage of dry age-related macular degeneration (AMD). Medidur is a tiny intravitreal insert designed to be injected intrvitreally. The insert then releases fluocinolone acetonide, a steroid, to the retina for up...

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Macugen
Dec 5, 2008
The ongoing VEGF Inhibition Study in Ocular Neovascularisation (VISION) clinical trial of Macugen (pegaptanib sodium) for age-related macular degeneration (AMD) has reported that no new safety concerns have emerged after 3 years of follow-up. Macugen was in 2004 the first anti-VEGF drug to be approved for the treatment of AMD in the United...

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Genentech
Nov 23, 2008
Lucentis (ranibizumab) appears safe in the treatment of wet age-related macular degeneration (AMD), according to an analysis of 4 large clinical trials. Dr David Boyer presented these findings at the 2008 Joint Meeting of the American Academy of Ophthalmology (AAO) and the European Society of Ophthalmology (SOE). Several clinical trials...

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Intravitreal injection
Nov 23, 2008
Medscape has assembled updates on several ongoing clinical trials into new drugs and dosing strategies that were presented at the 2008 Joint Meeting of the American Academy of Ophthalmology and the European Society of Ophthalmology held in November. Below is a synopsis of information presented. LEVEL Study The LEVEL study is evaluating the...

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Central retinal vein occlusion
Nov 12, 2008
Hot on the heels of last month's report that Avastin can improve vision and decrease macular edema in patients with non-ischemic central retinal vein occlusion, comes a Genentech-funded study that finds that Lucentis (ranibizumab) can do the same thing. Ten adult patients with macular edema associated with non-ischemic CRVO. Patients were...

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