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Displaying news items tagged with AMD (More tags »)
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Laboratory mouse
Feb 19, 2010
Albino rats develop progressive stages of retinal degeneration and CNV after long-term intense cyclic light exposure, allowing the detailed study of the pathogenesis and treatment of age-related macular degeneration (AMD), according to a new research report. Animal models of AMD that manifest some of the features of human AMD have become...

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Double helix DNA
Jan 27, 2010
RXi Pharmaceuticals Corporation, a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi), has announced a collaboration with Dr Shalesh Kaushal at The University of Massachusetts Medical School (UMMS). The research collaboration will be focused on the application of...

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The Iluvien insert, shown on a human finger to indicate size
Jan 27, 2010
Traditionally, ocular medications have been delivered through eye drops, intravitreal injections and systemic means. Now, various implants are being developed to deliver drugs for numerous indications. The main impetus for drug-eluting devices, especially in glaucoma, is patient noncompliance with dosing protocols, Steven D. Vold, MD, said....

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Alcohol bottles
Jan 27, 2010
Alcohol consumption was significantly associated with increased risk of incident early age-related macular degeneration in older women after adjusting for confounding factors, a study found. In addition, the study found that female subjects aged 80 years or older who smoked had a higher risk of early AMD than subjects who were younger than 80...

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Macular degeneration
Jan 24, 2010
Retinal vessel responses to flickering light are altered in patients with age-related macular degeneration (AMD) and are not improved after successful Avastin (bevacizumab) therapy. The retina has the ability to regulate blood flow in response to different metabolic demands. Several animal and human studies demonstrated an increase in retinal...

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Tags: Avastin, AMD

rheopheresis
Jan 24, 2010
Rheopheresis is capable of stabilizing dry age-related macular degeneration (AMD) and causing the resorption of soft drusen, according to a new study. Rheopheresis is a form of membrane differential filtration for the elimination of high molecular weight proteins from the blood. It is suggested that this process may improve the flow of blood...

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DNA double-helix molecule
Jan 21, 2010
The complement factor H genetic polymorphism rs1061170 is mostly involved in the onset of early age-related macular degeneration (AMD), while the age-related maculopathy susceptibility 2 (ARMS2) genetic varient rs10490924 is associated with the progression of early AMD to more advanced stages, according to a new study. The specific role of...

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Avastin
Jan 20, 2010
Avastin (bevacizumab) decreases survival of cultured retinal pigment epithelial cells stressed by hydrogen peroxide, according to a new study. Vascular endothelial cell growth factor (VEGF) is strongly induced by oxidative stress in retinal pigment epithelial (RPE) cells, and VEGF-A is a survival factor for various cell types. VEGF-A expression...

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DNA double-helix molecule
Dec 21, 2009
Genes that control toll-like receptors (TLRs), molecules located on the surface of cells that with play an important role in immunity, are not associated with risk for age-related macular degeneration (AMD), according to a new study. Epidemiologic studies suggest that personal risk factors (such as obesity), environmental risk factors (eg...

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Tags: AMD, genetics

Senior women
Dec 17, 2009
Low-dose aspirin has no effect on the risk of age-related macular degeneration (AMD) in adult women over 10 years of treatment and follow-up, according to a new research study. There are several possible pathways through which aspirin may exert a beneficial effect in AMD. At low doses (100 mg every other day), aspirin irreversibly inhibits...

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