MyVisionTest News Archive

Displaying news items tagged with wet AMD (More tags »)
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Feb 17, 2010
Maugen (pegaptanib sodium) is effective in real-world patients with treatment-naive neovascular age-related macular degeneration (NV-AMD) in uncontrolled community-based retina practices, according to a new study. Anti-VEGF treatments, such as pegaptanib sodium (Macugen), ranibizumab (Lucentis) and bevacizumab (Avastin), are the first...

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Japan
Feb 17, 2010
Lucentis (ranibizumab) is safe and effective for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients, according to the EXTEND-I clinical trial. Lucentis was approved for the treatment of wet AMD in Japan in January 2009. The application for approval in Japan was supported by the...

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Radiation warning symbol
Jan 27, 2010
Radiation therapy, when used to treat patients requiring chronic anti-VEGF therapy, may reduce the burden of treatment for neovascular age-related macular degeneration (AMD). According to results from a study presented by Dr Pravin Dugel at the joint meeting of the American Academy of Ophthalmology and Pan-American Association of Ophthalmology,...

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CATT trial logo
Jan 26, 2010
The first major clinical trial to compare bevacizumab and ranibizumab in a head-to-head fashion has completed enrollment, and the first data analysis is expected in about 1 year. Although the head-to-head comparison of Avastin (bevacizumab, Genentech) and Lucentis (ranibizumab, Genentech) in CATT (Comparisons of age-related macular degeneration...

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Age-related macular degeneration
Jan 26, 2010
A novel platelet-derived growth factor currently being studied in clinical trials may boost the effect of anti-VEGF therapy and provide a benefit in patients with choroidal neovascularization secondary to age-related macular degeneration, according to a speaker at the at Retina 2010 meeting. A phase 1 trial of E10030 (Ophthotech), a PDGF-B...

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submacular hemorrhage
Jan 26, 2010
Anticoagulants and antiplatelet agents are strongly associated with the development of large subretinal hemorrhages in age-related macular degeneration (AMD) patients, according to a new study. Patients with thick submacular hemorrhage complicating AMD typically have a poor visual prognosis. According to retrospective reports, the natural...

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Intravitreal injection
Jan 25, 2010
A flexible, individualized visual acuity-guided regimen after the three initial injections may sustain vision improvement with Lucentis (ranibizumab) and could improve cost-effectiveness and convenience and reduce drug administration–associated risks, according to a new study. In two phase 3 clinical trials, the time course of mean visual...

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Radiation warning symbol
Jan 23, 2010
Oraya Therapeutics announced that enrollment is now underway for a masked and sham-controlled study to demonstrate the efficacy and safety of radiation therapy for the treatment of wet age-related macular degeneration (AMD). The clinical trial is being conducted at seven European sites, and will include a minimum of 150 patients, with...

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Polypoidal choroidal vasculopathy
Jan 22, 2010
Among 20 patients with typical wet age-related macular degeneration (AMD) in one eye and polypoidal choroidal vasculopathy (PCV) in the other eye, 10 (50%) of the eyes with typical AMD developed PCV during an average follow-up period of 21.7 months, according to a new study. PCV is a distinct clinical entity that is characterized by polypoidal...

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Age-related macular degeneration
Dec 24, 2009
Ophthotech has received $30 million in Series B financing to support a phase 2 combination trial of E10030, the company's lead product candidate for treating age-related macular degeneration, the company announced. In a phase 1 combination study, E10030, an anti-platelet-derived growth factor (PDGF) aptamer, demonstrated effectiveness when...

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