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Displaying news items tagged with wet AMD (More tags »)
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Eye surgery
Dec 22, 2009
A new study finds that pars plana vitrectomy (ppV) with subretinal coapplication of recombinant tissue plasminogen activator (TPA) and Avastin (bevacizumab), and fluid–gas exchange improved visual acuity in most patients with neovascular age-related macular degeneration (AMD) with submacular haemorrhage (SMH). Eyes with large subretinal...

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Intravitreal injection
Dec 21, 2009
The MARINA and ANCHOR clinical trials of Lucentis (ranibizumab) therapy for exudative age-related macular degeneration (AMD) followed a fixed dosage regimen and fixed duration of 2 years. Hence, the trials did not provide any information about the “when to stop” endpoint. Because anti-VEGF drugs are angiostatic - they inactivate rather than...

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Japan
Dec 21, 2009
A study of the long-term effects of photodynamic therapy (PDT) on typical age-related macular degeneration (tAMD) and polypoidal choroidal vasculopathy (PCV) finds better visual outcomes in patients with PCV than on those with tAMD. Exudative AMD in the Japanese population is peculiar in that the frequency of polypoidal choroidal vasculopathy (...

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Polypoidal choroidal vasculopathy
Dec 17, 2009
A study from Japan finds that patients with polypoidal choroidal vasculopathy (PCV) are more likely to have a history of central serous chorioretinopathy (CSC) and significantly less likely to be diabetic than patients with typical age-related macular degeneration (AMD). Exudative AMD in the Japanese population is peculiar in that the...

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VEGF molecule
Dec 17, 2009
Intravitreal Lucentis (ranibizumab) injections in patients with neovascular AMD results in decreased aqueous levels of VEGF and increased levels of platelet-derived growth factor (PDGF). Methods and results In this prospective clinical trial 28 eyes of patients with neovascular AMD were compared with 28 eyes of age-matched patients with...

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Laser eye surgery
Dec 14, 2009
Intravitreal Avastin (bevacizumab) and low fluence photodynamic therapy (PDT) have a synergistic effect when applied together in the treatment of neonascular age-related macular degeneration (AMD), according to a new research report. PDT is performed by intravenous administration of a drug know as verteporfin, then activating the drug within...

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Pigment epithelial detachment
Nov 26, 2009
Lucentis (ranibizumab) is ineffective in treating avascular pigment epithelial detachment (PED) secondary to age-related macular degeneration (AMD) over a 1 year follow-up period, according to a new study. A PED occurs when fluid enters the space between the retinal pigment epithelium (RPE) and choroid (Figure). A serous PED is when aqueous...

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Visudyne
Nov 24, 2009
Intravitreal triamcinolone acetonide (ITA) does not improve the visual outcome of verteprofin photodynamic therapy (VPDT) for neovascular age-related macular degeneration (AMD), according to a new study. After the introduction of verteporfin for the treatment of subfoveal choroidal neovascularization (CNV), consideration was given to improving...

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VEGF-Trap
Nov 24, 2009
The CLEAR-IT 2 trial was a phase 2 study of the safety and efficacy of VEGF Trap-Eye in patients with neovascular age-related macular degeneration (AMD). An extension of the CLEAR-IT 2 trial followed patients from the original trial. Below are the results of the initial CLEAR-IT 2 as well as 6-month data from the extension stage. CLEAR-IT 2...

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Retinal angiomatous proliferation
Nov 19, 2009
Anti-VEGF monotherapy with Lucentis or Avastin represents a useful treatment option for patients with retinal angiomatous proliferation (RAP) associated with age-related macular degeneration (AMD), according to a new study. Retinal angiomatous proliferation is a distinct form of wet AMD associated with neovascularization that originates from...

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